MEDIA & PRESS UPDATES
March 9, 2020
ADAPTVAC’S GROUND-BREAKING TECHNOLOGY CENTRAL TO NEW €2.7M EU GRANT FUNDED COVID-19 VACCINE EFFORT
Hørsholm, Denmark, March 09, 2020 – AdaptVac announces that the company, as part of the PREVENT-nCoV consortium, has won a Horizon 2020 EU grant with total value of €2.7M. AdaptVac’s universal viral Capsid-Like Particle (CLP) will be employed to deliver an optimal vaccine against the SARS-CoV-2 virus ( COVID-19). The ambitious goal is to have the vaccine complete initial human clinical testing to show safety and efficacy within 12 months.
March 9, 2020
PREVENT-NCOV CONSORTIUM ANNOUNCES EU GRANT AWARD FOR COVID-19 VACCINE DEVELOPMENT PROGRAMME
Hørsholm, Denmark, March 09, 2020 – PREVENT-nCoV consortium announces awarding of EU Horizon 2020 grant for COVID-19 (SARS-CoV-2) Coronavirus vaccine development programme. The award amounts to 2,7 MEUR to develop and test the vaccine in PhI/IIa clinical studies within 12 months. The consortium members are AdaptVac; Institute for Tropical Medicine (ITM) at University of Tübingen; Department of Medical Microbiology, Leiden University Medical Center; Department of Immunology and Microbiology, University of Copenhagen; ExpreS2ion Biotechnologies; and Laboratory of Virology, Wageningen University.
February 26, 2020
ADAPTVAC SIGNS AV001 OPTION TO LICENSE AGREEMENT WITH EXPRES2ION
Hørsholm, Denmark, February 26, 2020 – AdaptVac announces that the company has signed an Option to License Agreement (“Agreement”) with ExpreS2ion Biotechnologies (“ExpreS2ion”) whereby ExpreS2ion may call an option to exclusively license in AV001 (HER2-cVLP), a preclinical-stage novel breast cancer vaccine candidate, which ExpreS2ion plans to develop towards human clinical studies. According to the Agreement, ExpreS2ion has the right to call the option to license in AV001 within 12 months. The option can entail a maximum amount of DKK 1.2M during the full option term.
February 25, 2020
DANISH AND DUTCH RESEARCH ORGANISATIONS RECEIVE A EUROSTARS GRANT FOR THE DEVELOPMENT OF A HIGHLY IMMUNOGENIC HER2-VACCINE AGAINST BREAST CANCER BY COMBINING THEIR STATE-OF-THE-ART TECHNOLOGIES
Hørsholm, Denmark; Oss, the Netherlands; February 25, 2020 – A consortium of Danish and Dutch research organisations led by AdaptVac ApS has been awarded a EUROSTARS grant for the further development of the AV001 vaccine against breast cancer. The combination of state-of-the art technologies revealed a highly immunogenic vaccine against human epidermal growth factor receptor 2 (HER2) expressed by cancer cells. With the support of EUROSTARS, we will be able to prove safety and immunogenicity in different in vivo models, finalize the production process and prepare for further clinical development. The envisaged vaccine could be an effective tool in the treatment of patients and in the delay of recurrence. The consortium consists of AdaptVac, ExpreS2ion Biotechnologies, and University of Copenhagen (Denmark), and LiteVax BV and the Biomedical Primate Research Centre (the Netherlands).
January 7, 2020
GRANTING OF ADAPTVAC’S CORE PLATFORM TECHNOLOGY PATENT IN THE UNITED STATES
Hørsholm, Denmark, January 07, 2020 – AdaptVac announces granting of its U.S. patent “Virus-like particle with efficient epitope display" by the USPTO. The patent provides intellectual property protection for the U.S. market of AdaptVac’s novel viral capsid-like particle (CLP) technology platform, and any vaccine produced using it (e.g. our Her2 immunotherapy, AV001). Furthermore, granting of the patent in the U.S. validates the patentability of AdaptVac’s technology platform patent portfolio, and represents a significant value inflection point for the company.
October 17, 2019
ADAPTVAC RECEIVES INNOBOOSTER GRANT TO SUPPORT PRE-CLINICAL DEVELOPMENT OF A HER2 VIRAL CAPSID-LIKE PARTICLE VACCINE (AV001)
Hørsholm, Denmark, October 17, 2019 – AdaptVac announces that it has been awarded an InnoBooster grant by the Danish Innovation Foundation worth 0.8M DKK. The grant provides further support for the viral-capsid based vaccine platform technology by potentially demonstrating a safe and effective treatment for pet dogs diagnosed with DER2+ cancer, the canine protein homologous to human epidermal growth factor receptor 2 (HER2). This project forms part of our pre-clinical development in support of a human clinical development program.
19 February, 2019
ADAPTVAC RECEIVES DKK 2.6 MILLION GRANT FOR VACCINE PROJECT TO DRAMATICALLY REDUCE ANTIBIOTIC USE IN THE SWINE INDUSTRY
Hørsholm, Denmark, February 19, 2019 – AdaptVac announces its participation in a new vaccine development project aimed at preventing post-weaning diarrhea (PWD), a major cause of antibiotic use in the swine industry. The project has been awarded a Grand Solutions grant worth DKK 11 million by the Danish Innovation Foundation, of which DKK 5 million supports Virus-Like Particle (VLP) platform technology development with DKK 2.6 million earmarked for AdaptVac.
20 December, 2018
ADAPTVAC RECEIVES INDUSTRIAL POST-DOCTORAL GRANT TO SUPPORT AV001 PRE-CLINICAL DEVELOPMENT
Hørsholm, Denmark, December 20, 2018 – AdaptVac announces that it has been awarded an Industrial grant by the Danish Innovation Foundation worth 1.2M DKK. The grant supports a three-year Ind. Post-Doctoral project focused on demonstrating AV001 as a safe and effective treatment for pet dogs diagnosed with HER2+ cancer. This project forms part of AV001’s pre-clinical development in support of AdaptVac’s human clinical development program.
20 December, 2018
ADAPTVAC RECEIVES INDUSTRIAL PHD GRANT AND INITIATES NEW VACCINE DEVELOPMENT RESEARCH PROGRAM IN CARDIOVASCULAR DISEASE
Hørsholm, Denmark, December 20, 2018 – AdaptVac announces that it has been awarded an Industrial PhD grant by the Danish Innovation Foundation worth DKK 1 million. The grant will support a three-year virus-like particle vaccine Ind. PhD research program focused on PCSK-9, a billion-dollar monoclonal antibody validated cardiovascular disease target.
10 September, 2018
GRANTING OF ADAPTVAC’S HER2 CANCER VACCINE PATENT IN THE UNITED STATES
Hørsholm, Denmark, September 10, 2018 – AdaptVac announces allowance of its U.S. divisional patent application “Virus-like particle with efficient epitope display" by the USPTO. The divisional patent provides intellectual property protection for the U.S. market of AdaptVac’s novel vaccine targeting HER2-positive cancer (AV001). Furthermore, allowance of the divisional patent in the U.S. validates the patentability of AdaptVac’s virus-like particle technology platform patent portfolio.
28 November, 2017
PROOF OF CONCEPT IN ANIMALS FOR ADAPTVAC’S BREAST CANCER VACCINE PUBLISHED IN SCIENTIFIC JOURNAL
AdaptVac announces that the scientific article "Virus-like particle display of HER2 induces potent anti-cancer responses" is published in the peer reviewed journal ´OncoImmunology´, and will be available online on November 28, 2017. The paper presents proof of concept in animals (POCA) for AV-001, AdaptVac’s novel vaccine targeting HER2 positive breast cancer tumours. The vaccine is demonstrated to be effective both in prevention and therapy of mammary carcinomas in HER2 transgenic mice.
18 October 2017
ADAPTVAC REACHES PROOF OF CONCEPT IN ANIMALS FOR BREAKTHROUGH BREAST CANCER VACCINE TREATMENT
AdaptVac announces that it has reached proof of concept in advanced animal models (POCA) for AV-001, its novel vaccine treatment against breast cancer tumours. This is a significant milestone for the Company in the progress towards clinical development. The Company will now initiate discussions with large pharmaceutical companies regarding a license or collaboration agreement for the clinical development of the project.